ABOUT US

 

Our DoverPac® Powder Handling Solutions

ILC Dover has been developing solutions for the pharmaceutical and biopharmaceutical markets since 1997.  We pioneered single use Flexible Containment to address safe powder handling of potent compounds and we’ve recently created a breakthrough solution (the EZ BioPac®) used in the efficient production of media and buffers for biopharmaceutical operations.  Through a strategic acquisition we also offer a full line of powder processing equipment.  All of our life science products leverage technology solutions from our product base including the space suits for NASA, advanced airships, and innovative respiratory protective equipment. 

To create the most effective single use solutions we’ve used our vast material development experience to create the ArmorFlex® line of films.  These regulatory compliant films are custom formulated by ILC to deliver superior elongation performance (nearly 500%) which translated into increased ruggedness and high strength. This feature coupled with a unique blend of safe and effective anti-static additives allows all of the DoverPac® products to deliver reliable high-level powder handling performance.

ILC’s manufacturing facilities include an ISO Class 7 Clean Room.  This clean room and our customized production equipment allow all of single use products to be produced to the most exacting standards.

PRODUCTS

Jet Breaker -  Deagglomeration Of Pharmaceutical Powders Jet Breaker - Deagglomeration Of Pharmaceutical Powders

De-agglomeration of powder blocs according to GMP standard.

Jet Feeder System for Powder Feeding and Mixing Jet Feeder System for Powder Feeding and Mixing

The Jet Feeder is a multi purpose system for feeding powders into liquid and for low shear mixing. It is the perfect unit to use on those products that are sensitive to shear. ILC Dover completed a successful test at a pharmaceutical facility for mixing starch into solution for a tableting process. The system is cGMP, easy to clean or CIP, and will work in single pass processes or recirculating processes. JetSolutions is an ILC Dover company and is the manufacturer of the Jet Feeder.

Pharmaceutical Containment of Powders Pharmaceutical Containment of Powders

Storage of pharmaceutical compounds is a function of the storage process and not a specific containment driven requirement per se. This is the case whether you are processing in a contained fashion or performing non-contained processing into open kegs with simple drum liners.

Single Use Biopharmaceutical Powder Handling Equipment Single Use Biopharmaceutical Powder Handling Equipment

ILC Dover brings a unique history and skill set to the biopharmaceutical industry, particularly single use biopharmaceutical powder handling and containment equipment.

Intermediate Bulk Containers for Bulk Liquid Handling Intermediate Bulk Containers for Bulk Liquid Handling

Buckhorn reusable intermediate bulk containers from Grayling Industries are designed to provide maximum product protection, hygiene, and efficiency.

EZ BioPac™: Powder Transfer Process EZ BioPac™: Powder Transfer Process

Advanced Powder Transfer for Media and Buffer preparation and Solids additions.

CrimpLoc™ Closure System CrimpLoc™ Closure System

ILC Dover pioneered flexible containment for the pharmaceutical industry and continues to innovate processes for better performance.

Containment: Pharmaceutical Powder Containment: Pharmaceutical Powder

ILC Dover has worked with our customers to develop Flexible Containment Solutions for a wide variety of processes within the pharmaceutical industry.

Disposable Conical Transfer Sleeve Disposable Conical Transfer Sleeve

Another proven method for cGMP processing is also available now using drums, a conical drum funnel and drum lifts.

Drum Transfer System Drum Transfer System
Flexible Containment for offloading drummed materials in a safe and efficient manner is provided by the Drum Transfer System (DTS) platform.
Containment: Granulator Technology Containment: Granulator Technology

Used for lab scale and production operations at multiple International Pharma manufacturers, our Granulator containment technology applications take the idea of retrofits to another level.

Process Area Barriers Curtains Process Area Barriers Curtains

Process Area Barrier Curtains are a useful tool in improving the containment levels in existing installations and as a method to restrict access.

Blending Containment Blending Containment

Our continuous liner system has been applied to production level V-Blenders. The low profile design was used in this application to support clearance limitations with this pre-installed piece of process equipment.

Containment: Offloading Containment: Offloading

Containment solutions for the contained offloading of Aurora Filters.

Containment: Bag In Bag Out Containment: Bag In Bag Out

The DoverPac® Bag In/Bag Out (BIBO) containment system is a family of contained transfer designs for multiple processes. The primary components for this validated operation consist of multiple groove canisters, docking interface hardware, and softgoods in either continuous liner form or discreet liners.

CONTAINMENT: Milling Powder CONTAINMENT: Milling Powder

Containment challenges are presented in a variety of ways by different types of particle reduction machines.

Crimping System Crimping System
Another ILC innovation in the area of flexible containment is the design of the advanced crimping system.
Drum Transfer Liners Drum Transfer Liners
Another proven method for cGMP processing is also available now using drums, a conical drum funnel and drum lifts. What makes this a viable approach is the use of ILC's disposable Conical Transfer Sleeve.
Contained Buffer And Media Prep Powder Addition Contained Buffer And Media Prep Powder Addition

ILC Dover supports the BioPharmaceutical Industry with cGMP processing for Buffer and Media prep. In order to make the move to closed processing at these steps in the process train, two distinct solutions have been implemented at various international manufacturers.

ArmorFlex® 114 Film: Containment Solution ArmorFlex® 114 Film: Containment Solution
At ILC Dover we are always “creating what’s next” by listening carefully to our customers. In response to customer input and emerging regulations we’ve developed a robust new film to support our DoverPac® Containment Systems. This revolutionary product, ArmorFlex® 114, delivers permanent static dissipative properties while meeting FDA and 2002/72/EC requirements for food contact and EP 3.1.3 test conditions.
Powder Containment Systems Powder Containment Systems
As the pioneer of flexible powder handling and containment systems in the pharmaceutical industry, ILC Dover has collaborated with hundreds of customers to provide engineered containment solutions for a wide range of process equipment. Many of these solutions address fine chemical powder handling, containment, and isolation needs.
Drum Sampling Enclosure System Drum Sampling Enclosure System
Sampling of active pharmaceutical ingredients, sensitizers, and other highly hazardous compounds for quality assurance purposes is a process that is performed on a routine basis.
Flexible Enclosures Flexible Enclosures
ILC Dover flexible enclosures take the concept of a traditional flexible glove bag to a new level. Using the same reliable fabrication techniques and proven containment design features found on our DoverPac® family of products, we’ve produced a line of flexible enclosures adaptable to a wide range of existing equipment.
DoverPac® SF DoverPac® SF
The DoverPac® SF replaces the rigid polybottle for split butterfly valve powder transfer applications.

ILC DOVER PRODUCTS - JETSOLUTIONS

Jet Breaker -  Deagglomeration Of Pharmaceutical Powders Jet Breaker - Deagglomeration Of Pharmaceutical Powders

De-agglomeration of powder blocs according to GMP standard.

Bag Filling of Pharmaceutical Powders Bag Filling of Pharmaceutical Powders

Thanks to its weighing terminal IT 9000 as well as its dosing device Multi-Dosimat, JetSolutions SA offers reliability and precision for filling powders or granulates into IBCs, boxes, bags, trucks, etc.

IBC Container Discharge Station IBC Container Discharge Station

The DOSICON discharge station has been developed and patented by JetSolutions SA for discharging the DOSICON containers (IBC).

Intermediate Bulk Container: DOSICON Intermediate Bulk Container: DOSICON

«IBC» means «Intermediate Bulk Container». An IBC is therefore a mobile, flexible and rapid storage device for any powder or granulates.

Powder Dosing Valve: DOSIMAT Powder Dosing Valve: DOSIMAT

The DOSIMAT valve allows a precise dosing of any powder or granulate when filling drums, bags, boxes, big-bags, etc.

Dust-Free Bulk Powder Transfer Dust-Free Bulk Powder Transfer

Dust-free bulk powder transfer from cardboard boxes, sacks or drums by means of a feed hopper with weighing frame. Positive raw material identification and registration by means of barcode scanners.

Jet Feed Injector (Powder to Liquid) System Jet Feed Injector (Powder to Liquid) System

The PST system can be operated in batch or continuous way. A set of valves allows the discharge or the re-circulation of the mixture. The powder characteristics and the flow capability will define whether a longer sucking time is required.

Multicomponent Dosing System Multicomponent Dosing System

The mixer is loaded with the individual raw materials exactly according to the formulation. The combination of Dosicon®  weighing equipment with suction conveying units fulfils this task. Fundamental advanrages of JetSolutions automatic multi-component dosing are high dosing accuracy (for quantities ranging from a few hundred grams to several hundred kilos), the prevention of cross-contamination risks, and freedom from dust.

Pharma Negative Pressure Conveyor for Powders Pharma Negative Pressure Conveyor for Powders

The negative pressure conveying is dedicated to small quantity of powder or granulates when:

Pharma Pneumatic Conveyor for Powders or Granules Pharma Pneumatic Conveyor for Powders or Granules

The pneumatic POSITIVE pressure conveying (or PRESSURE conveying) is dedicated  to the transfer of larger quantities of powder or granulates under following conditions:

Pharmaceutical Sampling Valves Pharmaceutical Sampling Valves

A manual or automatic sampling valve can be adapted at the hopper or container powder outlet with a standard containment or bottle system.

Pharmaceutical Homogenizer Pharmaceutical Homogenizer

The homogenizer is working as a particles size reducer for particles in suspension in a liquid and to calibrate their size at a defined value.

More From ILC Dover Products - JetSolutions

GRAYLING INDUSTRIAL PACKAGING PRODUCTS

Intermediate Bulk Containers for Bulk Liquid Handling Intermediate Bulk Containers for Bulk Liquid Handling

Buckhorn reusable intermediate bulk containers from Grayling Industries are designed to provide maximum product protection, hygiene, and efficiency.

CONTACT INFORMATION

ILC Dover

One Moonwalker Road

Frederica, DE 19946

UNITED STATES

Phone: 800-631-9567

Contact: Doug Dumey

FEATURED ARTICLES

  • Facing The Challenges: Single-Use Approaches To Powder Transfer
    Facing The Challenges: Single-Use Approaches To Powder Transfer

    Media and buffer preparation is a key part of the biopharmaceutical manufacturing process, and while it doesn’t have to be carried out in sterile conditions, improving the powder transfer process makes this step cleaner, safer, and more efficient, protects personnel and could cut time and costs as well. By Chris Rombach

  • Advanced Powder Transfer For Media And Buffer Preparation And Solids Additions

    ILC Dover has developed a new powder transfer process to solve issues related to contamination and reduce the fill time of each powder bag.

  • ArmorFlex® 110 Film Frequently Asked Questions

    At ILC Dover, we are always "creating what’s next" by listening carefully to our customers. In response to customer input and emerging regulations, we've developed a robust new film to support our DoverPac® Containment Solutions line. This revolutionary product, ArmorFlex® 110, delivers permanent static dissipative properties while meeting FDA and 2002/72/EC requirements for food contact.

  • Flexible Containment Solutions Guide: Mill Containment System - Jet Mills

    The process for this application consists of the controlled feeding of a mill through a feeder. The powder is introduced into the feeder using a drum transfer system.

  • Creating A Drum Transfer Solution
    Creating A Drum Transfer Solution

    One of the simplest, most convenient and most cost-effective ways to ship, receive, and store bulk powder ingredients, including active pharmaceutical ingredients (APIs), intermediates, excipients, and ingredients for buffers and media, is in drums. The contents of these will need to be transferred before use, and this process can be challenging. Integrated drum transfer solutions make the process simpler, cleaner, and faster, improving safety for both workers and patients, as well as protecting any remaining ingredients for storage.

  • Process Train Containment In CMO Operations

    Handling HP/C compounds requires highly specialized facilities and controls. As part of Pharmatek’s overall corporate safety program, they chose to integrate ILC Dover Flexible Containment Solutions into their HP/C facilities.

  • Q&A: 7 Things You Need To Know About Biopharmaceutical Powder Charging With Flexibles

    Alan George is the Product Manager for ILC Dover’s flexible containment and disposable systems and has been actively supporting the development of flexible containment solutions for a wide range of processing equipment for over 13 years. In this Q&A, Alan responds to 7 questions concerning the use of flexibles to support powder charging in biopharmaceutical operations.

NEWS

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