Manufacturing oligonucleotides commercially presents distinct challenges from those encountered at lab scale. Problems with synthesis are best addressed with a high degree of control and monitoring, making early process and technology optimization crucial.
Learn about high-performance and scalable THESYS™ OS oligosynthesizers, which feature advanced process controls and automation for efficient and reliable oligonucleotide synthesis.
Mid- to large-scale oligosynthesis has moved from legacy mixed bed reactors to more efficient flow-through column formats. Supported by decades of knowledge, these synthesis columns support your oligonucleotide production no matter how you have developed your synthesis process.
Our mid- to large-scale C&D Systems allow you to automate the cleavage and deprotection steps while increasing productivity by freeing up your oligosynthesizer to focus on its core job of synthesis.
Increase productivity in your purification processes with a range of liquid chromatography (LC) systems designed to unlock efficiencies in small molecule, peptide, oligonucleotide, and microbial-derived protein purification.
Check out how our optional stainless-steel bin works in conjunction with the DAC Ergo to capture spent media, and how one operator can even change over a column in as little as 15 minutes.
Discover the difference when skids are built with the understanding that oligonucleotides are unique therapeutics, demanding specialized and robust equipment to maximize every batch.