Silicone Molded Tubing Assemblies: A Solution For Reduced Contamination Risk And Greater Efficiency

By Roger Hendrick, Audrey Wipret

The adoption of single-use systems is one of today's most noteworthy trends in biopharmaceutical processing. The next-generation solution, molded tubing assemblies made of silicone, can help reduce the risk of contamination in biopharmaceutical and pharmaceutical processing. They can also make the process of producing drug products more efficient by replacing assemblies that incorporate separate thermoplastic components held in-place by tie wraps or other fasteners.

Greater demands are being placed on components of single-use disposable systems, including silicone tubing and fabricated tubing assemblies. This article focuses on Dow Corning® Pharma Fabricated Tubing Assemblies (FTAs) and reviews applications and benefits of these products in biopharmaceutical and pharmaceutical processing applications. It also identifies some of the most critical quality characteristics to consider when selecting components, such as silicone transport lines or molded silicone tubing connections, for single-use disposable applications.