Perfusion & Cell Retention System

The ATF™ System was originally designed for perfusion processes in mammalian cell culture, using hollow fiber filters to achieve an efficient cell separation with low shear and allowing robust large scale manufacturing. The filtration system was taken forward quickly as a preferred cell retention device and now is used in several large scale commercial perfusion facilities to manufacture proteins and antibodies.

The standard bioreactor types of glass in R&D and steel in pilot and production are easy to get an ATF System retrofitted to, with a range of standard adaptors and ports fitting all fermenter suppliers’ equipment, including Sartorius /Braun BBI, Applikon, New Brunswick, Bioengineering, Biolafitte/Pierre Guerin etc.