Datasheet | February 5, 2009

Datasheet: Aptuit's Maximum Exposure Service

Source: Aptuit, Inc.

In many cases, poor solubility of API (drug substance) limits exposure for toxicology, toxicokinetics studies, and clinical trials. Current estimates suggest that 80% of the new chemical entities are poorly soluble. The Aptuit maximum exposure (ME) service is a unique technology platform that utilizes a highly soluble amorphous dispersion or cocrystal to improve bioavailability for poorly soluble compounds. This strategy avoids complex solvent systems which can confound DMPK studies and clinical trials and provides a powder for testing via or al administr ation.

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