Technical Note: BioSC™ Sequential Multi Column Chromatography
Source: Novasep
SMCC uses the same type of stationary phase and the same separation techniques as used in any given batch
process. Three of the four columns
are available for loading in linear sequence while the fourth column is eluted, regenerated and equilibrated. This
happens asynchronously out of sequence with the continuing loading phase until it is ready to return to the
linear sequence in its proper turn.
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