Datasheet: Assessment Of Potential To Prolong QT Interval

The ICH S7B guidelines highlight the importance of understanding the consequences for development of a drug candidate with a potential to prolong QT interval. Cardiovascular assessment in vivo along with in vitro assessment at the HERG channel is recommended. If results from these two tests are equivocal then further investigation in other models are advised. Aptuit provide a fully comprehensive package of studies to cover ICH S7B regulatory requirements, which can be monitored for GLP compliance.