(S)-3,5-Dihydroxyphenylglycine
Source: Tocris Cookson, Inc.
Highly selective for PI-linked mGluRs in rat hippocampus and guinea pig cerebellum where it is more potent than (1S,3R)-ACPD
(S)-3,5-DHPG
(S)-3,5-Dihydroxyphenylglycine
M.W. 183.16
Desiccate at -20°C
Soluble to 100 mM in water; do not dissolve in base
Solutions may be stored at -20°C for up to 1 week
[162870-29-3]
Specific group I mGlu receptor agonist. <>
Highly selective for PI-linked mGluRs in rat hippocampus and guinea pig cerebellum where it is more potent than (1S,3R)-ACPD. Has minimal effects on cAMP-linked mGluR second messenger systems. Reported to be an antagonist of mGluRs linked to phospholipase D (PLD) in rat hippocampus.
Unit Sizes: 5 mg, 10 mg
Tocris Cookson, Inc., 114 Holloway Road, Suite 200, Saint Louis, MO 63011. Tel: 636-207-7651; Fax: 636-207-7683.
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