Article: Single-Use Equipment Standardization — Possible Or Not? By Maik W. Jornitz, Vice President, G-CON LLC
Since the introduction of single-use technologies into the biopharmaceutical processes in the early 1990s, a multitude of supplier companies mushroomed. The result is that these vendors market many unique single-use product designs, which makes it a chore for an end user to choose and to find a second supply source. The debate is whether single-use systems can be standardized or not. It is an intense debate, as some end users believe standardization restricts their process needs, and most vendors think that they would lose the competitive edge if they cannot customize their assemblies.
Application Note: Scalable Expansion Of Human Pluripotent Stem Cells By Ruth Olmer, Christina Kropp, Claudia Huether-Franken, and Robert Zweigerdt, DASGIP Information and Process Technology GmbH an Eppendorf Company
The routine application of human pluripotent stem cells and their derivatives in regenerative medicine and innovative drug discovery will require the constant supply of high cell numbers in consistent, high quality.
The Zeta Plus Encapsulated System consists of three product lines: A small system that is ideal for lab-scale production or scale-up studies, and two larger systems that are designed for production-scale biomanufacturing.
The DHX from ASI is a modular heat exchanger that employs a plate and frame concept, using a single-use bag as the sterile fluid path. The bags fit tightly between five dimpled, stainless steel plates efficiently transferring heat in a counter-current flow path. The system provides efficient, sterile heat transfer that easily integrates into any new and existing process.
New Brunswick's proprietary packed-bed impeller system is now available in a ready-to-use, labor-saving, single-use vessel. Achieve maximum cell densities and high yields without the traditional cost and time associated with cleaning and autoclaving between runs.
ProVance Protein A Columns are a portfolio of single campaign-use columns designed for GMP purification of monoclonal antibodies. Prepacked with Grace Protein A resin and available in a range of sizes, these columns expedite purification steps and help improve overall downstream productivity.
In this webinar you will learn about the Emphaze AEX Hybrid Purifier — a multimechanism clarification device that embodies the philosophy of innovation necessary to transform and redefine the mAb purification process.