How Stability Prediction Experiments Give You Confidence In Your ADCs

Stability experiments play a crucial role in the early stages of developing an antibody drug conjugate (ADC). These experiments leverage fluorescence and light scattering techniques to provide scientists with predictive insights into the conjugated molecule's behavior downstream, during optimization and delivery.

The data collected during stability experiments can mitigate stability problems during extended storage or high-concentration use of the ADC. This webinar explores how the Prometheus Panta supports several stability prediction experiments.

You'll learn:

• How to set up and interpret self-association experiments that provide insight into how your biologics will behave at clinically-relevant concentrations
• How thermal unfolding information from nanoDSF is used to measure kinetic stability, and make predictions about long-term storage stability
• Why these predictive stability experiments are so critical to undertake early in the development process