Product/Service

Formoterol hemifumarate

Source: Tocris Cookson, Inc.
Potent, selective and long-acting b2-adrenoceptor agonist. Displays 330-fold selectivity for b2 over b1 receptors (pKd values are 8.12 and 5.58 respectively). Active in the nanomolar range in isolated tissue

Catalogue Number: 1448
Name: Formoterol hemifumarate
Unit Size: 10mg, 50mg
Price (Dollars): $80, $360

Compound:
Formoterol hemifumarate
BD 40A / (R*,R*)-N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl] amino]ethyl]phenyl] formamide hemifumarate

M.W. 402.45
Store at RT
Soluble to 25 mM in water and to 50 mM in DMSO
[43229-80-7]

Pharmacological Action:
Potent, selective and long-acting b2-adrenoceptor agonist. Displays 330-fold selectivity for b2 over b1 receptors (pKd values are 8.12 and 5.58 respectively). Active in the nanomolar range in isolated tissue (pD2 = 9.29 for relaxation of guinea-pig trachea), and is longer-acting and 100-fold more potent than salbutamol. Anti-inflammatory and widely used for the treatment of asthma.

Tocris Cookson, Inc., 114 Holloway Road, Suite 200, Saint Louis, MO 63011. Tel: 636-207-7651; Fax: 636-207-7683.