Facilitating Production Of Cell Banks Using An Automated Cryovial Dispenser

By Stephen Guy, Dave Thomas, and Miriam Foster

The rapid aseptic preparation of cryovials is vital for the generation of high quality cell banks. Issues exist with standard manual methods as they are prone to variation, place constraints on batch sizes, and repetitive tasks raise operator health concerns.

These can be overcome by the application of a simple bench top automated cryovial processing system, Fill-It. This system is capable of decapping, dispensing and capping multiple cryovials in parallel with minimal operator interaction. This poster describes the tests that have been conducted to show that the system is capable of producing high quality and high viability material in cryovials, improved consistency and shortened process times with the potential to increase batch sizes for cell banking and dramatically reduce QC costs.