Electrophoresis Assay
Trevigen's CometAssay provides reagents and slides for the analysis of DNA fragmentation associated with DNA damage
N/Aen's CometAssay provides reagents and slides for the analysis of DNA fragmentation associated with DNA damage. The comet assay or single cell gel electrophoresis assay is based on the alkaline lysis of labile DNA at sites of damage.
The unwound, relaxed DNA is able to migrate out of the cell during electrophoresis and can be visualized by green staining. Cells that have accumulated DNA damage appear as fluorescent comets with tails of DNA fragmentation or unwinding, whereas, normal undamaged DNA does not migrate far from the origin.
Each slide provides two sample surfaces treated to promote agarose adherence, and a hydrophobic barrier to allow treatment with DNA repair enzymes.
<%=company%> 8405 Helgerman Court, Gaithersburg, MD 20877. Tel: 301-216-2800; Fax: 301-216-2801.
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