Cedex Automated Cell CounterSource: Roche innovatis AG
The Cedex is the first automated cell counting system based on the well-established Trypan Blue exclusion method for determining cell viability. Designed by Innovatis AG in 1995, the proven technology has become the "Industry Gold Standard" in the pharmaceutical and biotechnology industries. Today, more than 600 systems are in operation world-wide.
Cell count and cell viability are two of the most important parameters in cell culture related production and research. Traditionally, these parameters are determined manually with the aid of a microscope and a hemacytometer after staining the cells with Trypan blue.
However, a manual counter is known to be time-intensive, user-dependent and not reliable.
The Cedex analyzer has automated the manual method in order to provide the user with more accurate and precise data about cell count, viability and additional important parameters within minutes.
Sample handling, staining, cell counting and graphical analysis of the results are performed automatically by the Cedex. The resultant data are self-explanatory and can easily be archived.
The optional MS 20 Multisampler can convey up to 20 samples in sequence to the Cedex measurement without the need for user interference.
The hardware can be easily integrated into existing networks. Integration of the Cedex technology into automated process lines can be achieved via a Telnet port (TCP/IP Protocol) based on a "Remote Control" software feature.
innovatis AG also offers integration services for existing Laboratory Information Management Systems (LIMS).
The Cedex technology has been proven to fit into GMP processes and complies with the requirements of 21 CFR Part 11.
Advanced software offers:
- Automated cell culture analysis
- Diameter, aggregate & compactness histogram
- Cultivation time chart
- Scheduler for cleaning & maintenance
- Database filter and database management system
- Drag and drop administration for users and user roles
- Integrated system suitability testing