In this webinar you will learn about the Emphaze AEX Hybrid Purifier — a multimechanism clarification device that embodies the philosophy of innovation necessary to transform and redefine the mAb purification process.
Lessons Learned Help Pfizer Accelerate Biotherapeutic Development By Rob Wright
Six of the seven blockbuster biotherapeutics belonging to Big Pharma have roots to small biotechs. So too does Tim Charlebois, Ph.D., VP of technology and innovation strategy within Pfizer’s biotherapeutics pharmaceutical sciences (BTx Pharm Sci).
Application Note: Minimizing Purification Bottlenecks While Achieving Maximum Sample Recovery By Scott Anderson, Kathy Lawrence, Dennis McCreary, and Melissa Wilcox, Grace
By using the RevealX detection technology of the Reveleris system, which independently triggers fraction collection from multiple detectors including UV and ELSD, this work will demonstrate that these bottlenecks can be reduced or eliminated without reducing the recovery of compounds of interest.
Application Note: Process-Scale Antibody Purification By GE Healthcare Life Sciences
This application note describes a three-step purification process of a domain antibody (Dab) expressed in the periplasm of E. coli. First, a capture step using Capto L was used to reduce E. coli. host cell proteins (ECP) and endotoxin levels. Next, a polishing step using Capto MMC ImpRes further reduced ECP and endotoxin levels at yields of > 86%. Finally, Capto adhere ImpRes was run in flow-through mode to render product with undetectable endotoxin levels and ECP content of < 10 ppm.
White Paper: Mixing Predictions Without A Mixer By ASI Life Sciences
The purpose of the Computational Fluid Dynamics (CFD) Study was to predict the mixing performance of ASI's imPULSE Single-Use Mixing System across a range of small, medium, and large-scale vessels and fluid viscosities.
At the heart of the Envirotainer solution is Active Cold Chain Services, where customers can take advantage of the company's knowledge and expertise in healthcare transportation by working with a dedicated team of specialists.
This webinar will look at a project to automate a single-use, final bulk filtration and dispense processing step at Fujifilm Diosynth Biotechnologies, a biopharmaceutical contract manufacturing organization. The decision-making process used to proceed with the project, the project execution, and the outcomes of the project will all be described.