Advances In Downstream Single-Use Technologies Enable Greater Process Control And Higher Protein TitersSource: Thermo Fisher Scientific (Formerly ASI)
By Derek Masser, ASI Life Sciences
Downstream protein purification (the stage in which a protein is isolated and purified) is one of the last steps in biotherapeutic manufacturing. Single-use technologies are an increasingly popular choice for both upstream and downstream bioprocessing because they offer significant benefits over traditional multiuse manufacturing systems. Single-use technologies also provide an array of logistical benefits, including reduced costs, minimized risk of crosscontamination, and improved operational efficiency.